TABLE OF CONTENTS
| FOREWORDS | ||||||
| By Prof. Alain Pompidou, Member of the European Parliament | 12 | |||||
| INTRODUCTION | ||||||
| O. Ferrer-Roca | 14 | |||||
| Definitions References THE AUTHORS | 16 17 18 | |||||
| CHAPTER 1.
        HISTORY OF TELEMEDICINE M. Sosa-Iudicissa, R. Wootton, O. Ferrer-Roca | ||||||
| 1.1.
        Introduction and Perspectives 1.2. An overview and early experiences 1.3. Main phases in view of the prevailing technologies | 23 24 24 | |||||
| 1.3.1.
        Preelectronic 1.3.2. Electronic 1.3.3. Telegraphy 1.3.4. Telephony 1.3.5. Radio 1.3.6. Television 1.3.7. Wireless | 24 25 25 25 25 26 26 | |||||
| 1.4. Relevant international and country developments | 26 | |||||
| 1.4.1. United
        States 1.4.2. United Kingdom 1.4.3. Germany 1.4.4. Japan 1.4.5. France - L.Lareng, M.Sosa-Iudicissa 1.4.6. Norway- S. Pederden 1.4.7. Portugal 1.4.8. Italy - C. Ruggiero, R. Sacile, M. Giacomini 1.4.9. Spain 1.4.10. Greece - D. Sotiriou 1.4.11. Canada 1.4.12. The Netherlands 1.4.13. Finland 1.4.14. Belgium 1.4.15. Austria - T. Mairinger 1.4.16. China 1.4.17. Arab Countries 1.4.18. Russia 1.4.19. Australia 1.4.20. Iceland 1.4.21. Sweden | 27 28 29 29 29 30 30 31 32 33 35 35 35 36 36 36 36 37 37 37 37 | |||||
| 1.5. Conclusions 1.6. References and Bibliography | 38 38 | |||||
| CHAPTER 2.
        MINIMAL TECHNICAL REQUIREMENTS O. Ferrer-Roca, A. Sousa Pereira | ||||||
| Introduction 2.1.- Type of information to be sent and Standards used | 40 41 | |||||
| 2.1.1. Audio 2.1.2. Data | 41 42 | |||||
| Standards : EDI,
        UN-EDIFACT Systems EHCR Electronic Cards Medical Vocabulary DSS | 42 43 44 44 45 45 | |||||
| 2.1.3. Fax 2.1.4. Still Images : DICOM and other standards 2.1.5. CSCW , Computer supported co-operative work 2.1.6. Video | 46 47 50 51 | |||||
| Standard
        Encoding protocols Standard Image formats | 51 51 | |||||
| Analogue Digital : H.2xx, MPEG, Streaming, DVB | 51 51 | |||||
| 2.2.- Types of communications and networking | 55 | |||||
| 2.2.1. Networking architecture | 55 | |||||
| Structured
        Cabling ISO model | 55 57 | |||||
| 2.2.2. POTS | 57 | |||||
| Developments : ADSL, Internet Telephony | 58 | |||||
| 2.2.3. ISDN 2.2.4. ATM | 59 60 | |||||
| 2.2.4.1.
        Problems link to ATM 2.2.4.2. Standards | 60 61 | |||||
| 2.2.5. Other
        Fixed Networks 2.2.6. AIR/ Wireless Communications | 62 62 | |||||
| 2.2.6.1. Radio
        frequency. R. Luraschi 2.2.6.2. Microwaves transmission | 63 66 | |||||
| LANs connectivity | 66 | |||||
| 2.2.6.3. Satellite | 66 | |||||
| Orbital Geostationary | 67 68 | |||||
| 2.2.6.4. GSM 2.2.6.5. Cellular Digital Packet Data ( CDPD ) Strength and weaknesses of various technical solutions | 68 70 72 | |||||
| 2.3.- Acquisition and Display | 73 | |||||
| 2.3.1. Acquisition systems | 73 | |||||
| 2.3.1.1.
        Cameras: CRT, CCD, CMOS 2.3.1.2. Scanners | 73 73 | |||||
| Image Quality | 74 | |||||
| 2.3.1.3. Other specialised acquisition systems | 74 | |||||
| 2.3.2. Display systems | 75 | |||||
| 2.3.2.1.
        Analogue devices 2.3.2.2. Liquid Crystal Displays 2.3.2.3. Laser Displays 2.3.2.4. Holographic representations 2.3.2.5. Virtual Screen Devices | 75 78 79 79 79 | |||||
| 2.4.- Computation and Storage Systems | 79 | |||||
| 2.4.1. Computer
        speed up systems 2.4.2. Storage systems | 79 80 | |||||
| 2.4.2.1.
        Magnetic systems 2.4.2.2. Mixed Systems 2.4.2.3. Optical systems ( Laser devices ) 2.4.2.4. Solid State disks 2.4.2.5. Experimental storage systems | 80 81 81 81 81 | |||||
| 2.5. Human and
        organisational factors 2.6. Legal aspects References | 82 82 82 | |||||
| CHAPTER 3. MAIN
        TELEMEDICINE APPLICATIONS O. Ferrer-Roca | ||||||
| Introduction Teleradiology C. Ruggiero | 84 86 | |||||
| Definition Basic Parts of a Teleradiology system I.- Image Acquisition and management II.- Display systems III.- Communication Network IV.- Interpretation section | 86 86 86 89 90 90 | |||||
| Telepathology O. Ferrer-Roca | 91 | |||||
| Introduction Applications Requirements | 92 92 92 | |||||
| 1.- Multimedia
        Data Base 2.- Colour Images | 93 93 | |||||
| 2.1. Dynamic
        Range 2.2. Spatial Resolution 2.3. Compression Methods | 93 93 94 | |||||
| 3.- Interactive
        control of colour 4.- Controlled sampling 5.- Security and confidentiality tools | 94 95 95 | |||||
| Telequantization at distance | 96 | |||||
| Telecytology S. Markidou, P. Karakistos, A. Pouliakis | 97 | |||||
| Definition Applications | 97 97 | |||||
| Telecardiology D. Sotiriu | 99 | |||||
| Introduction Main requirements Examples Portable solutions | 99 99 101 101 | |||||
| Tele-home care C. Ruggiero, R. Sacile, M Giacomini | 102 | |||||
| Introduction Technical aspects Home based applications Telealarm Tele-home care Cost Savings Case example | 102 102 103 103 104 104 104 | |||||
| Teleoncology. C. Ruggiero, R. Sacile, M Giacomini | 106 | |||||
| Introduction F.
        Puglisi Advantages Applications Area of Domain Diagnostic aspects Teleradiology Telepathology Prognostic factors Terapeutical aspects Follow up aspects Data Bases | 106 107 107 108 108 108 108 109 109 109 111 | |||||
| Telesurgery O. Ferrer-Roca | 112 | |||||
| Introduction Minimum requirements | 112 112 | |||||
| Telepsychiatry O. Ferrer-Roca | 113 | |||||
| Introduction Specific requirements | 113 113 | |||||
| Teledermatology R. Wootton, M Loane | 115 | |||||
| Introduction Techniques | 115 115 | |||||
| Store and
        forward teledermatology Real-time teledermatology | 115 115 | |||||
| Conclusions | 116 | |||||
| Primary Care O. Ferrer-Roca | 117 | |||||
| Computer based
        health records Minimal injury Units Telephonic medicine | 117 118 118 | |||||
| Telephonic Medicine O. Ferrer-Roca | 118 | |||||
| Introduction Applications | 118 119 | |||||
| CHAPTER 4: BASIC KNOWLEDGE OF MULTIMEDIA COMMUNICATIONS | ||||||
| Introduction 4.1. Some Technical Terms 4.2. Network classification 4.3. Categories of Multimedia Communications 4.4. Protocol Hierarchies for Multimedia Communications 4.5. The H.320 series ( Videophone based ISDN ) 4.6. The T.120 series of recommendations 4.7. The H.324 series ( Videophone on PSTN ) 4.8. The H.323 series ( Videophone over LANs and the Internet ) 4.9. Media coding | 121 122 122 124 125 126 127 129 129 130 | |||||
| 4.9.1. Media
        coding for still images 4.9.2. Media coding for audio 4.9.3. Media coding for motion video 4.9.4. How does still image coding work ? 4.9.5. How does motion video coding work ? | 130 131 132 133 135 | |||||
| CHAPTER 5:
        QUALITY CONTROL AND QUALITY ASSURANCE IN TELEMEDICINE O. Ferrer-Roca. | ||||||
| Introduction 5.1. Controlled variables 5.2 Control case management 5.3. Sufficient data for analysis 5.4. Serious and appropriate statistical analysis | 137 137 138 138 138 | |||||
| 5.4.1. Analysis
        of concordance -precision - reproducibility 5.4.2. Analysis of validity 5.4.3. Cost-Benefit Analysis 5.4.4. Cost-Efficacy | 139 139 140 141 | |||||
| 5.5. Indications and Limitations | 142 | |||||
| CHAPTER 6:
        INTERNET IN TELEMEDICINE V. Della Mea | ||||||
| 6.1.- The
        Internet 6.2.- Basic concepts 6.3.- Security issues | 144 145 147 | |||||
| 6.3.1. Secure
        sockets layer 6.3.2. Firewalls and proxies | 147 147 | |||||
| 6.5.1. Internet
        electronic mail 6.5.2. Group collaborations : Newsgroups and mailing lists: | 147 149 | |||||
| 6.6.- Medical
        Data sharing : the WWW 6.7.- Forthcoming developments | 151 156 | |||||
| 6.7.1. IPv6 6.7.2. Real time transport in Internet 6.7.3. ATM 6.7.4. Agents | 156 157 157 157 | |||||
| 6.8.- Internet and Telemedicine | 158 | |||||
| 6.8.1.
        Telemedicine needs 6.8.2. E-mail applications for telemedicine 6.8.3. WWW applications in telemedicine | 158 158 159 | |||||
| 6.9.- Internet
        problems Conclusions | 159 159 | |||||
| CHAPTER 7:
        DISTANT TRAINING TELEWORKING AND TELETEACHING A. Kastania. | ||||||
| Introduction 7.1.- Organisational environments | 161 161 | |||||
| 7.1.1.
        Technology equipment and standards used 7.1.2. Manager 7.1.3. Studio 7.1.4. Staff | 162 165 165 167 | |||||
| 7.2.- Teleworking design and development | 167 | |||||
| 7.2.1.
        Definitions and importance 7.2.2. Usage guidelines and modalities | 167 168 | |||||
| Conclusion References | 168 169 | |||||
| CHAPTER 8. DATA
        SECURITY AND PRIVACY O. Ferrer-Roca, F. Allaert | ||||||
| Introduction 8.1.- Standards 8.2.- Mechanism of security | 170 171 172 | |||||
| 8.2.1.
        Encryption 8.2.2. Phases of encryption 8.2.3. Digital signature | 172 173 175 | |||||
| 8.3.- Security
        in Internet 8.4.- Security and Legal issues associated with CPR References | 176 179 181 | |||||
| CHAPTER 9:
        LIABILITY AND LEGAL ASPECTS O. Ferrer-Roca, F. Allaert | ||||||
| Introduction 9.1.- Main deontological applications | 182 182 | |||||
| 9.1.1. Security
        and privacy of medical data 9.1.2. Protection against malpractice | 182 183 | |||||
| 9.2.- Contract scenarios | 184 | |||||
| 9.2.1.
        Teleassistance 9.2.2. Teleconsultancy 9.2.3. Exceptions | 184 186 186 | |||||
| 9.3.- Legal
        protection 9.4.- Conclusions References | 186 187 187 | |||||
| CHAPTER 10.
        ECONOMICS AND MANAGEMENT IN TELEMEDICINE V. Strobl , O. Ferrer-Roca | ||||||
| 10.1.-
        Introduction 10.2.- Constrains | 189 190 | |||||
| 10.2.1. Linked
        to economy 10.2.2. Linked to acceptance | 190 191 | |||||
| 10.3.- Cost/Benefits | 192 | |||||
| 10.3.1. Source
        of Data 10.3.2. Difficulties in cost/benefit analysis | 192 193 | |||||
| 10.4.- Strategic Planning | 195 | |||||
| 10.4.1. Analysis
        situation and demands 10.4.2. Portfolio technique 10.4.3. Decision Theory 10.4.4. Cost/Benefits 10.4.5. Plan Implementation | 196 197 198 199 200 | |||||
| Conclusions References | 200 200 | |||||
| CHAPTER 11.
        SOCIAL ASPECTS AND TECHNOLOGY TRANSFER T. Mairinger, O. Ferrer-Roca | ||||||
| 11.1.-
        Definitions 11.2.- Introduction 11.3.- Forces affecting technology transfer 11.4.- Scenarios for Telemedicine Technology transfer 11.5.- Technology transfer requirements 11.6.- Strategy of Telemedicine Technology transfer 11.7.- Conclusions References | 201 201 202 204 205 206 207 207 | |||||
| CHAPTER 12.
        EMERGING ISSUES O. Ferrer-Roca, V. Della Mea | ||||||
| 12.1.-
        Multimedia packet oriented networks 12.2.- IP-Switching 12.3.- Virtual LANs 12.4.- MOS ( Multimedia Operating Systems ) 12.5.- Cellular digital packet data 12.6.- Agent technology V. Della Mea | 208 208 209 210 210 211 | |||||
| 12.6.1.
        Definitions 12.6.2. Functioning 12.6.3. Applications | 211 212 212 | |||||
| Brokers Health Care | 212 213 | |||||
| 12.6.4. Agent
        Languages 12.6.5. Standards | 213 214 | |||||
| ANNEX I.
        STANDARDISATION BODIES M. Sosa- Iudicisa, JL Monteagudo, O. Ferrer-Roca | ||||||
| I.1.-
        Introduction I.2.- Types of Standards I.3.- Standards and Telemedicine I.4.- Changing scenario I.5.- Impact on Telemedicine I.6.- Activities in Europe I.7.- Activities in the US I.8.- From research to market I.9.- Importance of participating I.10.- Other regulatory bodies I.11.- Conclusions References | 215 215 216 217 218 219 220 221 222 222 223 226 | |||||
| ANNEX II. MOST
        COMMON STATISTICAL EVALUATIONS O. Ferrer-Roca | ||||||
| II.1.- Two Binormal ROC-curve analysis | 228 | |||||
| II.1.1. Of
        Independent data sets II.1.2. Of Correlated data sets | 228 229 | |||||
| References | 230 | |||||
| ANNEX III. LIST
        OF NEW TERMS O Ferrer-Roca, M Sosa-Iudicissa | 231 | |||||
| ANNEX IV.-
        COLOUR THEORY O. Ferrer-Roca | ||||||
| IV.1.-
        Introduction IV.2.- Lights colours and colours of the objects IV.3.- Tridimentional representation of colours IV.4.- Colour spaces IV.5.- Response of the detectors | 236 236 237 238 238 | |||||
| IV.5.1. Gamma
        correction IV.5.2. Detector response | 238 240 | |||||
| IV.5.2.1. Light
        spectrum sensitivity IV.5.2.2. Densitometry | 240 241 | |||||
| References | 243 | |||||
| ANNEX V.
        NETWORKING SCHEMES O. Ferrer-Roca | ||||||
| V.1.- IEEE model
        for LANs V.2.- Requirements and network segmentation V.3.- Common Management Information Systems. P.Baquero | 244 245 246 | |||||
| ANNEX VI. TCP/IP
        FUNCTIONING O. Ferrer-Roca, V Della Mea | ||||||
| VI.1.-
        Transmission control protocols and IP protocols VI.2.- IP Addresses | 247 248 | |||||
| VI.2.1.
        Subnetwork mask VI.2.2. Network classes VI.2.3. Special conventions VI.2.4. Multiple IP addresses | 249 249 250 250 | |||||
| VI.3.- TCP
        Protocols VI.4.- TCP Commands | 251 252 | |||||
| VI.4.1. File
        transfer commands VI.4.2. Backup commands | 252 254 | |||||
| VI.5.- Other issues related with Internet | 255 | |||||
| VI.5.1.
        Codification of e-mails VI.5.2. Compression systems | 255 255 | |||||
| ANNEX VII.
        EXAMPLE QUESTIONNAIRE FOR TELEMEDICINE IMPLEMENTATION T. Mairinger | 257 | |||||
| ANNEX VIII.
        ELECTRONIC TRANSACTIONS. LEVELS OF PROTECTION O. Ferrer-Roca | ||||||
| VIII.1.-
        Introduction VIII.2.- Standards VIII.3.- Transactional issues in Internet VIII.4.- Levels of protection References | 261 261 261 264 264 | |||||
| ANNEX IX.
        PERCEPTION DIAGRAM O Ferrer-Roca | 265 | |||||
| ANNEX X. IMAGE
        FORMATS O. Ferrer-Roca, A. Sousa., R.J. Rodriguez | ||||||
| X.1.- GIF format | 267 | |||||
| X.1.1. Minimum
        format X.1.2. Image Definition X.1.3. Extensions | 268 269 269 | |||||
| X.2.- TIFF
        format X.3.- MPEG2 format | 271 272 | |||||
| X.3.1. MPEG2
        variants X.3.2. Differences between MPEG1 and MPEG2 | 273 273 | |||||
| X.4.- PNG format | 274 | |||||
| X.4.1. Chunks | 275 | |||||
| ANNEX XI. A BIT
        OF MATHS AND COMPUTERS E. Ruiz Enriquez | ||||||
| XI.1.- ASCII XI.2.- Binary notation XI.3.- Integer mathematics XI.4.- Prime numbers XI.5.- Blocks, Product Cipher and Cipher feed-back | 276 276 277 278 278 | |||||
| ANNEX XII. BROADCAST MULTIMEDIA | ||||||
| Introduction XII.1.- Broadcast multimedia communications: H.331 XII.2.- Future trends | 280 280 281 | |||||
| XII.2.1. Switched versus packed networks | 281 | |||||
| ANNEX XIII.
        LETTERS OF CONSENT SUBJECT INDEX | 283 285-309 | |||||